estrogen receptor-in-1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T60293	Estrogen receptor-IN-1
	Estrogen receptor-IN-1 (compound 16) is an effective estrogen receptor (ER) inhibitor with IC 50 s of 13, 5μM for ERα and Erβ, respectively [1].
T11237	Camizestrant	Estrogen receptor antagonist 2	Estrogen Receptor/ERR
	Camizestrant (Estrogen receptor antagonist 2) is an antagonist of the estrogen receptor and can be used in studies about ER+ HER2-advanced breast cancer[1].		Estrogen Receptor/ERR
T11236	Giredestrant tartrate	Estrogen receptor antagonist 1	Estrogen Receptor/ERR , Others
	Giredestrant tartrate (Estrogen receptor antagonist 1) is a novel, orally active, selective and effective non-steroidal estrogen receptor antagonist. Giredestrant tartrate strongly binds to ER, resulting in the failure o...		Estrogen Receptor/ERR , Others
T17252	SIM-688	SIM688	Estrogen/progestogen Receptor , NF-κB
	SIM-688 is a selective and orally active estrogen receptor inhibitor of NF-κB transcriptional activity (IC50 = 122 nM in HAECT-1 cells).		Estrogen/progestogen Receptor , NF-κB
T20625	Prochloraz	Sporgon,Prelude	Estrogen Receptor/ERR , AhR , Androgen Receptor , Antifungal
	Prochloraz (Prelude) is a broad-spectrum contact imidazole fungicide. Prochloraz inhibits human placental microsomal aromatase in vitro (IC50 = 40 nM). Prochloraz also acts as an estrogen receptor (IC50s = 25 μM) and and...
TN1567	Delphinidin chloride		Estrogen Receptor/ERR , VEGFR
	Delphinidin chloride, a natural plant pigment found in berries and red wine, is a precursor of certain anthocyanins. Delphinidin chloride induces the release of nitric oxide from the vascular endothelium, resulting in va...		Estrogen Receptor/ERR , VEGFR
T36914	2-Hydroxyanthraquinone		Others
	2-Hydroxyanthraquinone is an anthraquinone that has been found inSpermacoce latifoliaand has antibacterial and estrogenic activities.1,2It is active againstB. subtilisandB. cereus(MICs = 1.9 and 62.5 μg/ml, respectively)...		Others
T63582	Estrogen receptor antagonist 1
	Estrogen receptor antagonist 1 is a potent antagonist of the estrogen receptor. Estrogen receptor antagonist 1 has shown research potential in breast cancer disease.
T79064	Estrogen receptor modulator 7		Estrogen Receptor/ERR
	Estrogen Receptor Modulator 7 is a potent modulator of estrogen receptors, utilized in cancer research [1].		Estrogen Receptor/ERR
T14662	Bis-propargyl-PEG9		Others
	Bis-propargyl-PEG9 is a PEG-based PROTAC linker employed in the synthesis of PROTACs. It is specifically utilized to synthesize the bivalent ligands of estrogen receptor[1].		Others
T79109	Estrogen receptor modulator 8		Estrogen Receptor/ERR
	Estrogen Receptor Modulator 8 (compound 4) is an orally active inhibitor targeting Estrogen Receptor/ERR α with potent efficacy (IC50 = 0.437 nM in MCF-7 cells) and effectively hampers MCF-7 cell proliferation (IC50 = 0....		Estrogen Receptor/ERR
TN4383	Kazinol U		IL Receptor , IκB/IKK , NOS , NF-κB
	Kazinol U may have therapeutic value in delaying pancreatic β-cell destruction in type 1 diabetes by blocking the NF-ÎºB pathway in pancreatic β-cells reduces cell damage. Kazinol U shows estrogenic activity with ligand-...		IL Receptor , IκB/IKK , NOS , NF-κB
T25367	EM-800	EM800,EM 800
	EM-800 is a high affinity ligand for estrogen receptor-α (ERα), the prodrug of EM-652. EM-800 independently inhibited the growth of E1-stimulated ZR-75-1 xenograft tumors in nude mice.
T74857	ER degrader 5
	ER Degrader 5 is a potent compound that degrades the estrogen receptor (ER), exhibits anti-proliferation activity, and has potential applications in breast cancer research [1].
T74593	Taragarestrant meglumine
	Taragarestrant (D-0502) meglumine is a potent, orally active, and selective estrogen receptor degrader (SERD) demonstrating significant efficacy in ER+ breast cancer cell lines and xenograft models [1] [2].
T63675	ER degrader 1
	ER degrader 1 is a potent degrader of the estrogen receptor (ER). The estrogen signaling system plays an important role in the regulation of cell growth, differentiation and apoptosis, and ER degrader 1 has shown potenti...
T74221	ER degrader 2
	ER Degrader 2, a potent estrogen receptor (ER) degrader, plays a significant role in the estrogen signaling system, which is crucial for regulating cell growth, differentiation, and apoptosis. It holds promise for resear...
T74415	Imlunestrant tosylate
	Imlunestrant tosylate (LY-3484356) is a potent, orally active selective estrogen receptor degrader (SERD) exhibiting purely antagonistic properties. It effectively maintains inhibition of estrogen receptor (ER)-dependent...
T60674	DK1
	DK1 is a potent estrogen related receptor modulator. DK1 impacts the activity of ERRα receptor and reduces blood glucose. DK1 shows the potential in the diabetes research [1].
T82439	Estrogen receptor modulator 10		Estrogen Receptor/ERR
	Compound G-5b, an estrogen receptor modulator 10, functions as an estrogen receptor (ER) antagonist (IC50=6.7 nM) and degrader (DC50=0.4 nM). It has the capability to induce apoptosis and block cells at the G1/G0 phase, ...		Estrogen Receptor/ERR